Protease

Ottimo

Esfoliante

Protease at a glance

  • Name for a diverse group of enzymes
  • Found in animals, plants, bacteria, and fungi
  • Break down proteins and peptides
  • Help skin shed old and damaged tissue

Protease description

Protease is perhaps better known by its plural form proteases or as proteolytic enzymes. The name protease covers a large number of enzymes that break down proteins and peptides into shorter peptides or amino acids. These enzymes are made by plants, animals, fungi, and bacteria. In the human body proteases function to inhibit the function of certain proteins, break down inactive proteins into active peptides, and serve as an agent to kickstart certain biological processes. In the world of dermatology, proteases have been used in cleansers to remove “dirt” proteins (as in the proteins naturally found in soil) from skin. In leave-on formulations, proteases can help remove old, dead skin cells to reduce skin flaking and help moisturizers work better to restore skin’s barrier, particularly if it’s naturally deficient in the proteins that help keep it strong. In essence, proteases help skin’s surface with the natural process of desquamation – also known as exfoliation. Extensive research has not been conducted yet showing how effective proteases are in direct comparison to “chemical” exfoliates such as AHAs and BHA. Still, these ingredients are helpful in maintaining skin’s normal balance, which is always a good thing. Rather than replacing chemical exfoliants, using products with proteases can help boost their skin-renewing properties.

Protease references

  • Journal of Cosmetic Dermatology, August 2022, pages 3,300-3,307
  • Molecular Medicine Reports, August 2013, pages 551–556
  • Journal of Clinical and Experimental Dermatology, June 2013, pages 14–22
  • Journal of Biological Chemistry, November 2008, pages 30,433–30,437
  • Dermatologic Surgery, February 2005, pages 139-148

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Valutazione degli ingredienti

Ottimo

Comprovati e sostenuti da studi indipendenti. Ingrediente attivo eccezionale per la maggior parte dei tipi di pelle o dei problemi.

Buono

Necessario per migliorare la consistenza, la stabilità o la penetrazione di una formula.

Discreto

Generalmente non irritante, ma può presentare problemi per come appare esteticamente, nella stabilità o avere problemi di altro tipo che ne limitano l'utilità.

Da evitare

Può causare irritazioni. Il rischio aumenta se combinato con altri ingredienti potenzialmente problematici.

Non usare

Può causare irritazioni, infiammazioni, secchezza, ecc. Può offrire benefici solo in alcuni casi, ma nel complesso è dimostrato che fa più male che bene.

Sconosciuto

Non abbiamo trovato l'ingrediente nel nostro dizionario. Registriamo di volta in volta tutti gli ingredienti mancanti per tenere aggiornato il nostro dizionario.

Non classificato

Non abbiamo ancora assegnato un voto a questo ingrediente perché non abbiamo avuto modo di esaminare la ricerca in merito.